Patients with atrial fibrillation (chaotic heart rhythm) are at increased risks of clot formation and stroke, and therefore require anti-coagulation therapy with potent blood thinners (for example with drugs like warfarin, rivaroxaban, apaxiban etc.). This in turn increases the risk of bleeding events (including bleeding in the brain) which could be life-threatening.

The Watchman LAA closure therapy is where an umbrella-like device is placed percutaneously (minimally invasively) in a left heart chamber to reduce clot formation and thus reduce the risk of stroke. It has been shown to be an alternative to treatment with lifelong potent blood thinners.